(1) | 21.34/-0.1 | CBP | Romell Glave | (Croydon Harriers) | 1 FINAL | Kingsmeadow Stadium | 14 May 2017 |
(2) | 21.38/+0.1 | CBP | Josh Street | (South London Harriers) | 1 HEAT 1 | Kingsmeadow Stadium | 13 May 2012 |
(3) | 21.41/+0.9 | CBP | Harry Aikines-Aryeetey | (Sutton & District AC) | 1 FINAL | Kingsmeadow Stadium | 14 May 2006 |
(4) | 21.43/-0.5 | | Josh Street | (South London Harriers) | 1 FINAL | Kingsmeadow Stadium | 13 May 2012 |
(5) | 21.5/+0.4 | CBP | Donovan Reid | (Shaftesbury Harriers) | 1 FINAL | Motspur Park | 16 May 1981 |
| 21.5/-0.4 | | Christopher Lambert | (Belgrave Harriers) | 1 FINAL | Kingsmeadow Stadium | 8 May 1999 |
(7) | 21.64/0.0 | | Marvin Popoola | (Herne Hill Harriers) | 1 FINAL | Kingsmeadow Stadium | 25 May 2014 |
(8) | 21.65 | | Dele Onifade | (Herne Hill Harriers) | 1 FINAL | Kingsmeadow Stadium | 11 May 2008 |
| 21.65/-1.0 | | Dylan Da Costa | (Croydon Harriers) | 1 FINAL | Kingsmeadow Stadium | 13 May 2018 |
(10) | 21.66/0.0 | | Harry Aikines-Aryeetey | (Sutton & District AC) | 1 FINAL | Kingsmeadow Stadium | 15 May 2005 |
(11) | 21.77/+0.7 | | Marvin Popoola | (Herne Hill Harriers) | 1 HEAT 1 | Kingsmeadow Stadium | 25 May 2014 |
(12) | 21.8y | CBP | Mel Cheskin | (Hercules AC) | 1 FINAL | Motspur Park | 3 June 1961 |
| 21.8 | | Michael St Louis | (Herne Hill Harriers) | 1 FINAL | Motspur Park | 15 May 1982 |
| 21.8/-0.1 | | Michael St Louis | (Herne Hill Harriers) | 1 FINAL | Motspur Park | 21 May 1983 |
| 21.80 | | Simeon Ramsey-Graham | (Herne Hill Harriers) | 1 FINAL | Kingsmeadow Stadium | 9 May 2010 |
(16) | 21.81/-1.2 | | Josh Street | (South London Harriers) | 1 FINAL | Kingsmeadow Stadium | 15 May 2011 |
(17) | 21.84/-0.2 | | Josh Street | (South London Harriers) | 1 FINAL | Kingsmeadow Stadium | 26 May 2013 |
(18) | 21.86/-1.5 | | Brook Cronin | (Walton AC) | 1 HEAT 2 | Kingsmeadow Stadium | 14 May 2023 |
(19) | 21.9 | CBP | Mike Powell | (Hercules Wimbledon AC) | 1 HEAT 2 | Motspur Park | 10 May 1979 |
| 21.9/-0.5 | | Jason Livingston | (Croydon Harriers) | 1 FINAL | Tooting Bec | 20 May 1989 |
(21) | 21.91/1.5 | | Freddie Arkell | (Hercules Wimbledon AC) | 1 FINAL | Kingsmeadow Stadium | 15 May 2022 |
(22) | 21.94/-2.2 | | Daniel Luke | (Croydon Harriers) | 1 FINAL | Kingsmeadow Stadium | 24 May 2015 |
| 21.94 | | Dylan Da Costa | (Croydon Harriers) | 1 HEAT 2 | Kingsmeadow Stadium | 13 May 2018 |
(24) | 21.95/-0.7 | | Freddie Arkell | (Hercules Wimbledon AC) | 1 FINAL | Kingsmeadow Stadium | 14 May 2023 |
(25) | 21.96/-0.3 | | Derek Kinlock | (Croydon Harriers) | 1 FINAL | Kingsmeadow Stadium | 12 May 2019 |
(26) | 21.98/-0.3 | | Dylan Da Costa | (Croydon Harriers) | 2 FINAL | Kingsmeadow Stadium | 12 May 2019 |
(27) | 21.99/+0.9 | | Idowu Akindele | (Sutton & District AC) | 2 FINAL | Kingsmeadow Stadium | 14 May 2006 |
(28) | 22.02/-0.5 | | Lolu Oluwole-Ojo | (Windsor, Slough, Eton & Hounslow AC) | 2 FINAL | Kingsmeadow Stadium | 13 May 2012 |
| 22.02/-1.0 | | Micah Francis-Dwyer | (Croydon Harriers) | 2 FINAL | Kingsmeadow Stadium | 13 May 2018 |
| 22.02/+0.8 | | Jack N'Douba | (Blackheath & Bromley Harriers AC) | 1 HEAT 2 | Kingsmeadow Stadium | 12 May 2024 |
(31) | 22.03/-1.0 | | Alex Hanson | (Woking AC) | 3 FINAL | Kingsmeadow Stadium | 13 May 2018 |
(32) | 22.04/-1.0 | | James Hanson | (Woking AC) | 4 FINAL | Kingsmeadow Stadium | 13 May 2018 |
| 22.04 | | Jack N'Douba | (Blackheath & Bromley Harriers AC) | 1 FINAL | Kingsmeadow Stadium | 12 May 2024 |
(34) | 22.06/-0.1 | | Samir Williams | (Croydon Harriers) | 2 FINAL | Kingsmeadow Stadium | 14 May 2017 |
(35) | 22.07 | | Stedson Dockery | (Herne Hill Harriers) | 2 FINAL | Kingsmeadow Stadium | 11 May 2008 |
(36) | 22.09/-2.2 | | Frederick Afrifa | (Crawley AC) | 2 FINAL | Kingsmeadow Stadium | 24 May 2015 |
(37) | 22.1/+2.9 | CBP | Rod Milne | (Guildford & Godalming AC) | 1 FINAL | Motspur Park | 15 May 1976 |
| 22.1 | | Mike Powell | (Hercules Wimbledon AC) | 1 FINAL | Motspur Park | 12 May 1979 |
| 22.1 | | Michael Powell | (Shaftesbury Harriers) | 1 HEAT 2 | Motspur Park | 12 May 1981 |
| 22.1/-0.1 | | Richard Haizelden | (Sutton & Cheam Harriers) | 2 FINAL | Motspur Park | 21 May 1983 |
| 22.1w/+2.24 | | Jason Hallifax | (Hercules Wimbledon AC) | 1 FINAL | Motspur Park | 17 May 1986 |
| 22.1/+0.2 | | Jason Livingston | (Croydon Harriers) | 1 S-FINAL 2 | Tooting Bec | 20 May 1989 |
| 22.10/0.7 | | Freddie Arkell | (Hercules Wimbledon AC) | 1 HEAT 2 | Kingsmeadow Stadium | 15 May 2022 |
(44) | 22.11/-2.7 | | Tyler Panton | (Woking AC) | 1 FINAL | Kingsmeadow Stadium | 1 August 2021 |
(45) | 22.12/0.0 | | Ryan Thomas | (unattached) | 2 FINAL | Kingsmeadow Stadium | 15 May 2005 |
(46) | 22.17/+1.3 | | Tremayne Gilling | (Sutton & District AC) | 1 HEAT 1 | Kingsmeadow Stadium | 10 May 2009 |
(47) | 22.18/-0.5 | | Tucker Bryant | (Kingston AC & Polytechnic Harriers) | 3 FINAL | Kingsmeadow Stadium | 13 May 2012 |
(48) | 22.19/+3.4 | | Lawrence Mensah | (Herne Hill Harriers) | 1 FINAL | Kingsmeadow Stadium | 11 May 2003 |
| 22.19/-0.4 | | Tremayne Gilling | (Sutton & District AC) | 1 FINAL | Kingsmeadow Stadium | 10 May 2009 |
(50) | 22.2y | CBP | Clive Ryan | (Belgrave Harriers) | 1 FINAL | Motspur Park | 1 June 1957 |
| 22.2/+0.6 | | John Gostelow | (Hercules Wimbledon AC) | 1 FINAL | Motspur Park | 30 May 1970 |
| 22.2 | | Michael Powell | (Hercules Wimbledon AC) | 1 FINAL | Motspur Park | 17 May 1980 |
| 22.2 | | Richard Haizelden | (Sutton & Cheam Harriers) | 1 FINAL | Motspur Park | 19 May 1984 |
| 22.2/+0.6 | | Christopher Lambert | (Belgrave Harriers) | 1 FINAL | Kingsmeadow Stadium | 10 May 1998 |
| 22.20/-2.2 | | Cameron Starr | (Sutton & District AC) | 3 FINAL | Kingsmeadow Stadium | 24 May 2015 |
|
55 performances of 22.20 or better. |